Tyrosine kinase-IN-7 (compound 13h) is an inhibitor of the tyrosine kinase EGFR. The IC50s for inhibiting EGFR(WT) and EGFR(T790M) are 0.630 µM and 0.956 µM respectively. Tyrosine kinase-IN-7 has antitumor activity against four cancer cell lines (HepG2, HCT-116, MCF-7, and A431) with IC50s of 13.02 µM, 10.14 µM, 12.68 µM, and 47.05 µM, respectively[1].
Molecular Weight:
297.37
Purity:
99.25
CAS Number:
[345615-74-9]
Formula:
C16H15N3OS
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
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