HS-291 is a HtpG inhibitor of Borrelia burgdorferi (Bb). HS-291 contains BX-2819 (high affinity for Bb HtpG), PEG linker, and Verteporfin (HY-B0146) (a photoactive toxin).HS-291 produces reactive oxygen species under light activation to oxidize HtpG and a discrete protein subset near chaperone proteins and can quickly and irreversibly inactivate Bb[1].
Molecular Weight:
2961.44
Formula:
C156H194N18O36S2
Target:
Bacterial,ROS Kinase
Application Notes:
MCE Product type: Reference compound1
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