TrxR-IN-6 (compound 1d) is a TrxR inhibitor that induces reactive oxygen species (ROS) accumulation and has anticancer activity. TrxR-IN-6 can further lead to redox system collapse, inducing mitochondrial dysfunction, endoplasmic reticulum (ER) stress, and DNA damage. Finally, it causes oxidative stress and induces apoptosis[1].
Molecular Weight:
384.18
CAS Number:
[3032446-53-7]
Formula:
C11H12AsCl2NOS2
Target:
Apoptosis,TrxR
Application Notes:
MCE Product type: Reference compound
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