IBL-302 (AMU302) is an orally available dual-signaling inhibitor of PIM and PI3K/AKT/mTOR with activity against breast cancer and neuroblastoma. IBL-302 demonstrated in vivo efficacy in a nude mouse xenograft model, inhibiting trastuzumab (HY-P9907) resistance challenges. IBL-302 also enhances the effects of common cytotoxic chemotherapy drugs cisplatin (HY-17394), doxorubicin (HY-15142A), and etoposide (HY-13629)[1][2][3].
Molecular Weight:
567.63
Purity:
98.21
CAS Number:
[1414455-21-2]
Formula:
C25H18FN5O4S3
Target:
Akt,mTOR,PI3K,Pim
Application Notes:
MCE Product type: Reference compound1
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