Glycyl H-1152 hydrochloride (compound 18) is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride. Glycyl H-1152 hydrochloride inhibits ROCKII, Aurora A, CAMKII and PKG, with IC50s of 0.0118, 2.35, 2.57 and 3.26 µM respectively. Glycyl H-1152 hydrochloride has higher selective than H-1152 hydrochloride[1].
Molecular Weight:
449.40
Purity:
99.9
CAS Number:
[913844-45-8]
Formula:
C18H26Cl2N4O3S
Target:
Aurora Kinase,CaMK,ROCK
Application Notes:
MCE Product type: Reference compound
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