RIPK2-IN-5 (compound 14) is a high affinity and excellent selectivity RIPK2 inhibitor with an IC50 value of 5.1nM. RIPK2-IN-5 has cellular anti-inflammatory effect and can reduce the secretion of MDP-induced TNF-alpha with a dose-dependent manner. RIPK2-IN-5 shows moderate stability in human liver microsome. RIPK2-IN-5 can be used for the research of immune diseases[1].
Molecular Weight:
354.43
Purity:
99.73
CAS Number:
[2885227-09-6]
Formula:
C21H14N4S
Target:
RIP kinase
Application Notes:
MCE Product type: Reference compound
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