AChE-IN-51 (compound 8C) is an orally active, non-competitive inhibitor of AChE and BChE (IC50: 84 nM, 97 nM). It also inhibits MMP-2 and amyloid Abeta1-42 aggregates (IC50: 724 nM, 302 nM). AChE-IN-51 has low cytotoxicity and in silico predicted blood-brain barrier permeability. Can be used for research on diseases such as Alzheimers disease (AD)[1].
Molecular Weight:
344.39
Formula:
C23H21OP
Target:
Amyloid-beta,Cholinesterase (ChE),MMP
Application Notes:
MCE Product type: Reference compound
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