RIPK1-IN-19 is a selective RIPK1 inhibitor (IC50=15 nM). RIPK1-IN-19 does not show obvious activity against RIPK2, RIPK3, and RIPK4. RIPK1-IN-19 displays potent protective activity in TNFalpha-induced systemic inflammatory response syndrome (SIRS) model and Imiquimod (IMQ)-induced psoriasis model. RIPK1-IN-19 can be used in research on inflammation and immune system diseases[1].
Molecular Weight:
496.54
Purity:
98.87
CAS Number:
[2763831-43-0]
Formula:
C28H25FN6O2
Target:
RIP kinase
Application Notes:
MCE Product type: Reference compound1
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