JNJ-40411813 (ADX-71149) is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM. JNJ-40411813 has orally bioactivity and penetrate the blood-brain barriers. JNJ-40411813 has the potential property of anti-depression[1][2][3].
Molecular Weight:
344.88
Purity:
99.85
CAS Number:
[1127498-03-6]
Formula:
C20H25ClN2O
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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