Antitumor agent-133 (compound 4d) is a bis-isatin derivative, with activities against Huh1 (IC50=17.13 µM) and Huh7 (IC50=8.27 µM). Antitumor agent-133 induces cell autophagy and inhibits tumor growth through regulation of LC3BII, ATG5 and p62 proteins[1].
Molecular Weight:
692.31
Formula:
C27H24Br2N4O8
Target:
Atg8/LC3,Autophagy,p62
Application Notes:
MCE Product type: Reference compound
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