Osimertinib (mesylate) (Standard) is the analytical standard of Osimertinib (mesylate). This product is intended for research and analytical applications. Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].
Molecular Weight:
595.71
Purity:
99.93
CAS Number:
[1421373-66-1]
Formula:
C29H37N7O5S
Target:
EGFR,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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