Osimertinib (Standard) is the analytical standard of Osimertinib. This product is intended for research and analytical applications. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].
Molecular Weight:
499.61
Purity:
99.69
CAS Number:
[1421373-65-0]
Formula:
C28H33N7O2
Target:
EGFR,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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