Osimertinib-d6 is a deuterium labeled osimertinib. Osimertinib is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].
Molecular Weight:
505.64
Purity:
99.70
CAS Number:
[1638281-44-3]
Formula:
C28H27D6N7O2
Target:
EGFR
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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