K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM. K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor activity[1].
Molecular Weight:
348.46
CAS Number:
[1309444-75-4]
Formula:
C18H24N2O3S
Target:
Apoptosis,SphK
Application Notes:
MCE Product type: Reference compound
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