K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity[1].
Molecular Weight:
384.92
Purity:
99.63
CAS Number:
[1449240-68-9]
Formula:
C18H25ClN2O3S
Target:
Apoptosis,SphK
Application Notes:
MCE Product type: Reference compound
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