Menin-MLL inhibitor-25 (compound A6) is a potent Menin-MLL interaction inhibitor with an IC50 value of 0.38 µM. Menin-MLL inhibitor-25 shows anti-proliferative activity. Menin-MLL inhibitor-25 induces apoptosis and cell cycle arrest at G0/G1 phase. Menin-MLL inhibitor-25 reverses the differentiation arrest[1].
Molecular Weight:
481.57
Formula:
C28H28FN7
Target:
Apoptosis,Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound1
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