DSP-0390 is an orally effective inhibitor of Emopamil-binding protein (EBP). DSP-0390 blocks the cholesterol de novo synthesis pathway in tumor cells by inhibiting EBP, and demonstrates significant anti-tumor activity in an orthotopic xenograft model of glioblastoma (GBM). DSP-0390 can be used for the study of recurrent high-grade gliomas[1].
Molecular Weight:
415.96
CAS Number:
[2376765-57-8]
Formula:
C23H30ClN3O2
Target:
Emopamil Binding Protein
Application Notes:
MCE Product type: Reference compound
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