HMC-B17 is a selective, orally bioavailable HPK1 inhibitor (IC50 = 1.39 nM) that potentiates anti-PD-L1 efficacy. HMC-B17 potently enhances the IL-2 secretion in Jurkat cells (EC50 = 11.56 nM). HMC-B17 can be used for the research of cancer[1].
Molecular Weight:
427.54
CAS Number:
[2935913-83-8]
Formula:
C27H29N3O2
Target:
MAP4K
Application Notes:
MCE Product type: Reference compound
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