SHP2-IN-26 (Compound 4b) is a highly selective SHP2 allosteric inhibitor with a IC50 value of 3.2 nM. SHP2-IN-26 inhibits the phosphorylation of ERK and AKT in NCI-H358 cells. SHP2-IN-26 has antitumor activity[1].
Molecular Weight:
465.40
Formula:
C20H22Cl2N6OS
Target:
Phosphatase,SHP2
Application Notes:
MCE Product type: Reference compound
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