Elobixibat-d5 is the deuterium labeled Elobixibat (HY-15790). Elobixibat (A 3309, AZD 7806) is orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to treat metabolic syndrome. Elobixibat can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly[1][2][3][4].
Molecular Weight:
700.92
Formula:
C36H40D5N3O7S2
Target:
Apical Sodium-Dependent Bile Acid Transporter,Isotope-Labeled Compounds
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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