CYP1B1-IN-7 (compound 2a) is a selective inhibitor of CYP1B1 (IC50: 75 nM). CYP1B1-IN-7 also reverses resistance (IC50: 29 µM) and exhibits cytotoxicity in the CYP1B1-overexpressing MCF-7 cell line that is resistant to Docetaxel (HY-B0011)[1].
Molecular Weight:
292.76
Purity:
99.88
CAS Number:
[52601-58-8]
Formula:
C19H13ClO
Target:
Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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