JJC8-089 is a dopamine transporter (DAT) inhibitor that may improve motivational dysfunction and increase effortful behavior in goal-directed activities. JJC8-089 significantly reversed the low-effort effects induced by the VMAT-2 inhibitor Tetrabenazine (HY-B0590) in rats and increased the choice of high-effort fixed-ratio 5-bar presses versus food intake. [1][2].
Molecular Weight:
406.53
CAS Number:
[1627576-64-0]
Formula:
C22H28F2N2OS
Target:
Dopamine Transporter
Application Notes:
MCE Product type: Reference compound1
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