B-Raf IN 17 (Compound 8e) is a potent and orally active type II multi-kinase inhibitor. B-Raf IN 17 exhibits potent cellular-level suppression of BRAFWT, VEGFR-2, and FGFR-1 in A375 cell line, with IC50 values of 0.02, 0.18 and 1.65 µM, respectively. B-Raf IN 17 can be used for the research of cancer[1].
Molecular Weight:
460.28
Formula:
C22H14BrN5O2
Target:
FGFR,Raf,VEGFR
Application Notes:
MCE Product type: Reference compound
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