TOPOI/PARP-1-IN-1, CAS [[2948352-16-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-158138
Supplier Catalog Number:
HY-158138
Alternative Catalog Number:
MCE-HY-158138-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
TOPOI/PARP-1-IN-1 (Compound B6) is an orally active, low cytotoxic TOPOI/PARP dual inhibitor with an IC50 value of 0.09 µM for PARP1. TOPOI/PARP-1-IN-1 can effectively inhibit the proliferation and migration of cancer cells. TOPOI/PARP-1-IN-1 also causes cell cycle arrest in the G0/G1 phase and induces apoptosis. The tumor growth inhibition rate (TGI) of TOPOI/PARP-1-IN-1 in mice is 75.4%[1].
Molecular Weight:
718.52
CAS Number:
[2948352-16-5]
Formula:
C36H38Br2N4O2
Target:
Apoptosis,PARP,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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