PROTAC CRBN ligand-2 (12) is a Biguanide-PROTAC derivative, with an EC50 of 0.15 mM in KP4 cells. PROTAC CRBN ligand-2 (12) demonstrates the ability to alter levels of mitochondrial proteins, notably complexes I and IV[1].
Molecular Weight:
666.64
Formula:
C33H30N8O8
Target:
Ligands for E3 Ligase
Application Notes:
MCE Product type: Reference compound
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