CVN293 is a selective and brain permeable potassium ion (K+) channel KCNK13 inhibtor with IC50s of 41 nM and 28 nM for hKCNK13 and mKCNK13, respectively. CVN293 potently inhibits the NLRP3-inflammasome mediated production of the proinflammatory cytokine IL-1beta in microglia[1].
Molecular Weight:
311.27
Purity:
99.91
CAS Number:
[2815296-08-1]
Formula:
C14H10FN7O
Target:
NOD-like Receptor (NLR),Potassium Channel
Application Notes:
MCE Product type: Reference compound
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