CNB-001 is a potent and orally active 5-lipoxygenase (5-LOX) inhibitor. CNB-001 can decreases 5-LOX expression and increase proteasome activity. CNB-001 can inhibit accumulation of soluble Amyloid-beta and ubiquitinated aggregated proteins. CNB-001 can inhibit apoptosis, ROS production and stabilize mitochondrial membrane potential. CNB-001 can reduce insulin resistance and increase glucose uptake. CNB-001 also exhibits anti-ischemic, anti-inflammatory effects. CNB-001 can be used for the researches of inflammation, neurological and metabolic disease, such as Alzheimers disease, stroke and diabetes[1][2][3][4].
Molecular Weight:
440.49
Purity:
90.70
CAS Number:
[1019110-87-2]
Formula:
C27H24N2O4
Target:
Amyloid-beta,Apoptosis,Lipoxygenase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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