BTL-MK (Compound 19) an orally active antiallergic agent, that inhibits degranulation of mast cells with an IC50 of 6.7 µM, through binding to the inhibitory receptor FcgammaRIIB. BTL-MK improves the metaboilic stability in human liver microsomes. BTL-MK ameliorates the allergic response in Ovalbumins (HY-W250978)-induced food allergy mice model. BTL-MK exhibits a good pharmacokinetic character with metabolic stability[1].
Molecular Weight:
408.44
CAS Number:
[2758569-43-4]
Formula:
C24H24O6
Target:
Fc Receptor (FcR)
Application Notes:
MCE Product type: Reference compound
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