Nesosteine (CO-1177) is a bronchitis inhibitor that improves the rheology and production of airway bronchial mucus in rabbits. Nesosteine significantly reduced the viscosity of airway bronchial mucus in animals with sulfuric acid nebulized bronchitis and increased mucus production in healthy animals. Nesosteine is more active than mucus-regulating drugs such as Sobrerol, N-acetylcysteine, bromhexine, ambroxol, S-carboxymethylcysteine, and mercaptoalanine. Nesosteine also reduced the content of total proteins in airway bronchial mucus, such as albumin, alpha1, alpha2, beta, and gamma mucins[1].
Molecular Weight:
259.26
Purity:
95
CAS Number:
[84210-62-8]
Formula:
C11H10NNaO3S
Target:
Histamine Receptor
Application Notes:
MCE Product type: Reference compound1
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