PROTAC ATM degrader-1 is a ATM PROTAC degrader with a KD value of 1.17 nM. PROTAC ATM degrader-1 triggers DNA damage response, cell cycle arrest, and apoptosis in cancer cells via the ubiquitin-proteasome-dependent degradation pathway. PROTAC ATM degrader-1 can be used for research on colorectal cancer[1].
Molecular Weight:
898.08
Purity:
98.01
CAS Number:
[2821804-13-9]
Formula:
C49H55N9O6S
Target:
Apoptosis,ATM/ATR,DNA/RNA Synthesis,PROTACs
Application Notes:
MCE Product type: Reference compound
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