PRDX1-IN-2 (compound 15) is a selective inhibitor of the antioxidant enzyme Peroxiredoxin 1 (PRDX1) (IC50=0.35 µM). PRDX1-IN-2 decreases the mitochondria membrane potential of SW620 cells, probably due to ROS induced by PRDX1 inhibition, leading to cell apoptosis. PRDX1-IN-2 can be used for colorectal cancer research[1].
Molecular Weight:
576.77
CAS Number:
[2566976-43-8]
Formula:
C35H48N2O5
Target:
Apoptosis,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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