CEP-37440 is a potent, orally active dual FAK/ALK inhibitor with IC50 values of 2.3 nM and 3.5 nM for FAK and ALK, respectively. CEP-37440 decreases the cell proliferation by blocking the autophosphorylation kinase activity of FAK1 (Tyr 397)[1][2].
Molecular Weight:
580.12
Purity:
99.91
CAS Number:
[1391712-60-9]
Formula:
C30H38ClN7O3
Target:
Anaplastic lymphoma kinase (ALK),FAK
Application Notes:
MCE Product type: Reference compound
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