Aurora kinase inhibitor-14, CAS [[958226-81-8]] Preis auf Anfrage

Product Overview

• Article Name: Aurora kinase inhibitor-14, CAS [[958226-81-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-158618
• Supplier Catalog Number: HY-158618
• Alternative Catalog Number: MCE-HY-158618-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Aurora kinase inhibitor-14 (Compound 79) is an orally active and highly selective inhibitor of Aurora kinases with IC50 values of 0.5 nM and 1.2 nM for Aurora A and Aurora B, respectively. Aurora kinase inhibitor-14 binds to the ATP-binding site of Aurora kinases to block chromosome segregation during mitosis and induce apoptosis in tumor cells. Aurora kinase inhibitor-14 is promising for research of various solid tumors and hematological malignancies, such as non-small cell lung cancer, breast cancer, and acute myeloid leukemia[1].

Product Properties

• Molecular Weight: 561.64
• CAS Number: [958226-81-8]
• Formula: C28H38F3N7O2
• Target: Apoptosis,Aurora Kinase

Application Notes

• Application Notes: MCE Product type: Reference compound1