TLR7 agonist 20 hydrochloride is an imidazoquinoline analogue. TLR7 agonist 20 hydrochloride is a potent TLR7 specific agonist, with an EC50 value of 0.23 µM for hTLR7. TLR7 agonist 20 hydrochloride shows strong adjuvant activity on spike antibody levels which induces a strong T helper 1 (Th1) response with increase in IgG2b and IgG2c, in addition to IgG1[1].
Molecular Weight:
396.91
Purity:
99.86
Formula:
C22H25ClN4O
Target:
Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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