PROTAC IRAK4 degrader-11 (compound 15) is PROTAC based on Cereblon ligand, and induces the degradation of IRAK4 with maximum degradation of 96.25% and the DC50 of 2.29 nM in HEK293 cells(Sturcture Note:(Blue: Cereblon ligand (HY-14658), Black: linker,Pink: IRAK4 inhibitor)[1].
Molecular Weight:
798.81
Formula:
C41H41F3N8O6
Target:
IRAK,PROTACs
Application Notes:
MCE Product type: Reference compound
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