PROTAC BET Degrader-12

Product Overview

• Article Name: PROTAC BET Degrader-12
• Biozol Catalog Number: MCE-HY-158764
• Supplier Catalog Number: HY-158764
• Alternative Catalog Number: MCE-HY-158764-50MG,MCE-HY-158764-5MG,MCE-HY-158764-25MG,MCE-HY-158764-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC BET Degrader-12 (Compound 8b) is a PROTAC degrader for bromodomain and extra-terminal domain (BET)-containing proteins, which degrades the BRD3 and BRD4 in a DCAF11-dependent manner. PROTAC BET Degrader-12 inhibits cell viability of KBM7 with a DC50 of 305.2 nM. (Pink: ligand for target protein (+)-JQ-1 (HY-13030), Black: linker (HY-159077), Blue: ligand for E3 ligase (HY-159076))[1]

Product Properties

• Molecular Weight: 867.46
• Purity: 98.10
• Formula: C48H47ClN8O4S
• Target: Epigenetic Reader Domain,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound1