PTC-209 hydrobromide is a specific BMI-1 inhibitor with an IC50 of 0.5 µM in HEK293T cell line. PTC-209 hydrobromide irreversibly impairs colorectal cancer-initiating cells (CICs). PTC-209 hydrobromide shows potent anti-myeloma activity and impairs the tumor microenvironment[1][2].
Molecular Weight:
576.10
Purity:
99.02
CAS Number:
[1217022-63-3]
Formula:
C17H14Br3N5OS
Target:
Autophagy,BMI1
Application Notes:
MCE Product type: Reference compound
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