MMs02943764 is a 1,2,4-triazole derivative with anticancer activity. MMs02943764 has significant antiproliferative effects on multiple cancer cell lines. PAC, a structural analog of MMs02943764, has significant cytotoxicity against the leukemia cell line K562 (IC50=35.264 µM), reduces the degradation of p53 by inhibiting Mdm2 and Pirh2, and induces K562 cell cycle arrest[1].
Molecular Weight:
551.45
Purity:
98
CAS Number:
[708287-29-0]
Formula:
C24H25BrF2N4O2S
Target:
MDM-2/p53
Application Notes:
Reference compound
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