GE1111 is the antagonist for mas-related G protein-coupled receptor X2 (MRGPRX2) with an IC50 of 9.42 µM. GE1111 inhibits mast cell degranulation with an IC50 of 4.7 µM. GE1111 exhibits anti-allergic and anti-inflammatory effects in C48/80 (HY-130592)-induced systemic allergic reaction model[1].
Molecular Weight:
466.48
Purity:
95.7300
CAS Number:
[2883669-12-1]
Formula:
C28H22N2O5
Target:
Mas-related G-protein-coupled Receptor (MRGPR)
Application Notes:
Reference compound
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