Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110alpha, p110beta, p110gamma and p110delta, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.
Molecular Weight:
270.29
Purity:
99.82
CAS Number:
[934493-76-2]
Formula:
C13H14N6O
Target:
mTOR,PI3K
Application Notes:
Reference compound
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