Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) is a conjugate of an ADC toxin Exatecan (HY-13631) and a linker Mal-Val-Ala-PAB-N(SO2Me). Mal-Val-Ala-PAB-N(SO2Me)-Exatecan can be used for synthesis of ADC FZ-AD005. FZ-AD005 is a delta-like ligand 3 (DLL3, KD=58.3 pM) targeting ADC, that exhibits antitumor efficacy against SCLC cancer[1][2].
Molecular Weight:
1141.22
Purity:
99.11
CAS Number:
[2575682-08-3]
Formula:
C56H65FN8O15S
Target:
Drug-Linker Conjugates for ADC
Application Notes:
Reference compound
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