RGB110 (Compound 10d) is a PROTAC inhibitor for D-dopachrome tautomerase with an IC50 of 5.9 µM. RGB110 causes no degradation of D-DT. (Pink: ligand for target protein (HY-159164), Black: linker (HY-W125017), Blue: ligand for E3 ligase CRBN (HY-10984))[1]
Molecular Weight:
814.77
Formula:
C40H37F3N8O8
Target:
PROTACs
Application Notes:
Reference compound
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