HbF inducer 3 (Compound dWIZ-2) is an orally active molecular glue, which degrades the WIZ transcription factor (DC50=13 nM in primary human erythroid precursor cell) and induces the expression of fetal hemoglobin (HbF) (EC50=100 nM). HbF inducer 3 exhibits good pharmacokinetic characteristics in cynomolgus monkeys[1].
Molecular Weight:
385.46
Purity:
99.38
CAS Number:
[2654011-51-3]
Formula:
C21H27N3O4
Target:
Histone Acetyltransferase,Molecular Glues
Application Notes:
MCE Product type: Reference compound1
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