hCAXII-IN-10 (Compound 18b) is a dual inhibitor of human carbonic anhydrase isoform XII (hCAXII) and cathepsin B, with a Ki value of 2.2 nM. hCAXII-IN-10 can inhibit the role of hCAXII in providing tumors with a pH microenvironment conducive to tumor growth, and is expected to be used in the study of tumor diseases[1].
Molecular Weight:
437.47
Formula:
C20H19N7O3S
Target:
Ser/Thr Protease
Application Notes:
MCE Product type: Reference compound1
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