BChE-IN-33 (compound 4r), an arylaminonaphthol derivative, is a potent butyrylcholinesterase (BChE) inhibitor with an IC50 of 14.78 µM. BChE-IN-33 also inhibits CYP2C19, CYP2C9, CYP2D6. BChE-IN-33 shows potent antioxidant activity with IC50 values of 150.48 µM, 2.56 µM and 4.61 µM by DPPH, ABTS, Ferric-phenanthroline assay, respectively. BChE-IN-33 has the potential for Alzheimer research[1].
Molecular Weight:
404.85
Formula:
C23H17ClN2O3
Target:
Cholinesterase (ChE),Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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