PQM-164 (Compound 3e) has antioxidant activity (IC50: 0.93 µM for DPPH radical). PQM-164 shows anti-inflammatory activity against 6-OHDA (HY-B1081A)-induced neuronal damage in activated microglial cells. PQM-164 decreases the accumulation of alpha-synuclein. PQM-164 promotes nuclear translocation of Nrf2 and its transcriptional activity. PQM-164 can be used for research of Parkinsons disease[1].
Molecular Weight:
342.35
CAS Number:
[2226535-25-5]
Formula:
C18H18N2O5
Target:
alpha-synuclein
Application Notes:
MCE Product type: Reference compound1
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