PSB-CB-27 is a potent and selective GPR18 inhibitor with an IC50 of 0.65 µM. PSB-CB-27 shows selectivity over Human GPR55, Human CB1 receptor, and Human CB2 receptor. PSB-CB-27 leads to a complete blockade of delta9-Tetrahydrocannabinol (THC)-induced GPR18 activation. PSB-CB-27 can be used for inflammatory diseases and cancer immunotherapy research[1].
Molecular Weight:
471.01
CAS Number:
[2237222-16-9]
Formula:
C25H27ClN2O3S
Target:
Orphan GPCR
Application Notes:
MCE Product type: Reference compound
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