XM-U-14, CAS [[3098519-83-3]] Preis auf Anfrage
Catalog Number:
MCE-HY-159175
| Article Name: |
XM-U-14, CAS [[3098519-83-3]] Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-159175 |
| Supplier Catalog Number: |
HY-159175 |
| Alternative Catalog Number: |
MCE-HY-159175-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| XM-U-14 is a selective PROTAC USP7 Degrader (DC50: 0.74 nM in inducing USP7 degradation in RS4,11 cell line). XM-U-14 upregulates the levels of p53 and p21. XM-U-14 also significantly inhibits acute lymphoblastic leukemia (ALL) cell growth (IC50: 0.5 nM and 8.3 nM for RS4,11 cells and Reh cells respectively). XM-U-14 induces apoptosis and cycle arrest. XM-U-14 inhibits tumor growth. (Blue: VHL ligand (HY-159465), Black: linker (HY-W539783), Pink: USP7 inhibitor (HY-159464))[1]. |
| Molecular Weight: |
1064.30 |
| CAS Number: |
[3098519-83-3] |
| Formula: |
C58H69N11O7S |
| Target: |
Apoptosis,Deubiquitinase,MDM-2/p53,PROTACs |
| Application Notes: |
MCE Product type: Reference compound |
