SBN-284 (compound 3x) is a dual inhibitor of blood-brain permeable Cholinesterases and the NLRP3 inflammasome and is effective against EeAChE, hAChE and eqBChE, the IC50 values of are 0.37, 0.31, 0.29 µM respectively, and the EC50 of NLRP3 inflamm is 1 µM. SBN-284 can be used in Alzheimers disease research[1].
Molecular Weight:
585.73
Formula:
C35H43N3O5
Target:
Cholinesterase (ChE),NOD-like Receptor (NLR)
Application Notes:
Reference compound
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