SDUY038 is a SHP2 allosteric inhibitor, with an IC50 of 1.2 µM and KD of 0.29 µM, respectively. SDUY038 exhibits pan-antitumor activity (IC50 = 7-24 µM) by suppressing pERK expression. SDUY038 exhibits t1/2 of 3.95 h by oral administration[1].
Molecular Weight:
385.31
CAS Number:
[2892720-11-3]
Formula:
C17H18Cl2N2O2S
Target:
SHP2
Application Notes:
MCE Product type: Reference compound
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